ABSTRACT
La paniculitis epiploica aislada es una entidad rara, mayormente observada en los adultos. Se presenta con inflamación del tejido adiposo del epiplón. Los síntomas varían entre manifestaciones locales (por ejemplo, dolor a la palpación abdominal o una masa palpable) y sistémicas, que incluyen dolor abdominal, dolor de espalda, fiebre, descenso de peso y trastornos intestinales. Presentamos este caso como una primera acción de sensibilización respecto de un caso de paniculitis epiploica en un niño, afección que debe tenerse en cuenta en el diagnóstico diferencial del íleo a fin de evitar cirugías innecesarias.
Isolated omental panniculitis is a rare entity mostly seen in adults. It presents with the inflammation of the fatty tissue of the omentum. The symptoms may vary from local (e.g. abdominal tenderness or palpable mass) to systemic manifestations including abdominal pain, back pain, fever, weight loss and bowel disturbances. We presented this case as a first awareness of omental panniculitis in a child which must be kept in mind at the differential diagnosis of ileus so that unnecessary surgeries might be avoided.
Subject(s)
Humans , Male , Adolescent , Panniculitis, Peritoneal/diagnosis , Panniculitis, Peritoneal/complications , Abdominal Pain/etiologyABSTRACT
Objectives: This retrospective study was designed to evaluate the importance of tissue expressions of caveolin‑1 (Cav‑1) and AT‑rich interactive domain 1 alpha (ARID‑1A) which are known as signal regulator and tumor suppressor in differential diagnosis of uterine smooth muscle tumors (SMTs). Materials and Methods: Thirty patients recently diagnosed as uterine SMTs at the Tepecik Training and Research Hospital were identified using pathology databases. Immunohistochemical stains for Cav‑1 and ARID‑1A were performed. Results: In this series, there were 10 leiomyosarcomas (LMSs), 10 uterine smooth muscle tumors of uncertain malignant potentials (STUMPs), and 10 leiomyomas (LMs). Cav‑1 expression located cytoplasmic or perivascular area. Cytoplasmic Cav‑1 expression was determined in 5 LMSs and 2 STUMPs while perivascular Cav‑1 expression was determined in 9 LMSs and 2 STUMPs. Statistically, it was determined that if the tumor becomes malignant and more invasive, it gains the perivascular Cav‑1 expression (P = 0.029). On the other hand, the mean nuclear staining rate for ARID‑1A in LMSs (63 ± 23.4%) was higher than both STUMPs (60 ± 18.5%) and LMs (34.5 ± 16.5%). Statistically, it was determined that the expression of ARID‑1A was significantly downregulated in LMs when compared with STUMPs and LMSs (P = 0.004). Conclusions: Our findings were demonstrated that perivascular Cav‑1 expression was seen to be a marker for malignancy of uterine SMTs. Similarly, we found to link of ARID‑1A expression and the aggressiveness of SMTs. Therefore, it may be suggested that Cav‑1 and ARID‑1A may act as predictive biomarkers in uterine SMTs.